API-1

API-1 is an Akt/protein kinase B (PKB) inhibitor, which binds the pleckstrin homology domain of Akt and blocks Akt membrane translocation, and inhibits EGF-induced kinase activity of Akt1, AKT2 and AKT3. Activity results in cell growth arrest and apoptosis in human cancer cells with constitutively active Akt.

Availability: In stock

Product Name Price Qty
API-1 10mg
$229.00

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Additional Info
Additional Info
Catalog No. ES2737
CAS Number 36707-00-3
Formula C13H15N5O6
M. Wt 337.29
Purity >98 %
Solubility Soluble to 100 mM in DMSO
Chemical Name 4-Amino-5,8-dihydro-5-oxo-8-β-D-ribo​furanosyl-pyrido[2,3-d]pyrimidine-6-carboxamide
Synonyms N/A
Storage Store at RT
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