Adrenergic Receptors
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A 61603 hydrobromide
A 61603 hydrobromide is a potent α-adrenoceptor agonist that is at least 35-fold more potent at α1A than at α1B or α1D sites. Learn MoreStarting at: $105.00
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(R)-(-)-Niguldipine hydrochloride
(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist; less active enantiomer. Learn MoreStarting at: $110.00
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(S)-(+)-Niguldipine hydrochloride
(S)-(+)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist; more active enantiomer. Learn MoreStarting at: $110.00
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3-MPPI
3-MPPI is a very potent ligand for α1 sites (Ki for displacement of prazosin = 0.2 nM) which displays different binding properties for each α1 subtype (pKi values are 8.74, 9.44 and 9.57 for α1B, α1D and α1A adrenoceptors respectively). Learn MoreStarting at: $100.00
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2-PMDQ
2-PMDQ is a potent and selective α1-adrenoceptor antagonist and antihypertensive. Learn MoreStarting at: $105.00
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2-MPMDQ
2-MPMDQ is a potent and selective α1-adrenoceptor antagonist; hypotensive. Learn MoreStarting at: $95.00
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SNAP 5089
SNAP 5089 is a subtype-selective α1A-adrenoceptor antagonist that displays > 600-fold selectivity over other adrenoceptors (Kivalues are 0.35, 220, 370, 540, 800 and 1200 nM for α1A, α1B, α2C, α1D, α2B and α2A subtypes respectively and 540 nM for L-type Ca2+ channels), which inhibits noradrenalin-induced contractions in rabbit vascular and lower urinary tissues. Learn MoreStarting at: $105.00
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Tizanidine hydrochloride
Tizanidine hydrochloride is a α2-adrenergic receptor agonist. Learn MoreStarting at: $42.00
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Yohimbine hydrochloride
Yohimbine hydrochloride is an α2-adrenoceptor antagonist. Learn MoreStarting at: $35.00
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ARC 239 dihydrochloride
ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist with pKD values of 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively. Learn MoreStarting at: $99.00
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JP 1302 dihydrochloride
JP 1302 dihydrochloride is a α2C-adrenoceptor antagonist that potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo. Learn MoreStarting at: $145.00
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Imiloxan hydrochloride
Imiloxan hydrochloride is a moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity. Learn MoreStarting at: $90.00
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SKF 86466 hydrochloride
SKF 86466 hydrochloride is a potent and selective α2 antagonist at pre- and post-junctional α2-adrenoceptors that exhibits antihypertensive activity in a rat model. Learn MoreStarting at: $115.00
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Efaroxan hydrochloride
Efaroxan hydrochloride is a potent, highly selective α2 adrenoceptor antagonist and imidazoline I1 receptor ligand. Learn MoreStarting at: $99.00
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(R)-(+)-m-Nitrobiphenyline oxalate
(R)-(+)-m-Nitrobiphenyline oxalate is a α2C-adrenoceptor agonist that potently inhibits cAMP accumulation in CHO cells with an EC50 value of 38 nM. Learn MoreStarting at: $149.00
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UK 14304
UK 14304 is a full α2 adrenergic agonist that is centrally active following systemic administration in vivo. Learn MoreStarting at: $89.00
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ST 91
ST 91 is a α2-adrenoceptor agonist that does not cross the blood brain barrier, which displays ~ 120-fold selectivity for α2 receptors over α1 receptors and acts predominantly at non-α2A-adrenoceptors which may be of the α2C subtype. Learn MoreStarting at: $99.00
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RX 821002 hydrochloride
RX 821002 hydrochloride is a potent, selective α2-adrenoceptor antagonist with very low affinity for imidazoline sites which displays selectivity for the α2D over the α2A subtypes (pKd values are 9.7 and 8.2 respectively). Learn MoreStarting at: $49.00
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Spiroxatrine
Spiroxatrine is a 5-HT1A antagonist, which is more active and selective than spiperone. Learn MoreStarting at: $85.00
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BRL 44408 maleate
BRL 44408 maleate is a selective α2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2A and α2B-adrenergic receptors respectively). Increases hippocampal noradrenalin release following systemic administration. Learn MoreStarting at: $100.00